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Jun 19, 2012
Implantable device helps Huntington's

Various studies suggest that certain "neurotrophic factors" could have a significant positive impact on patients suffering from Huntington's disease. Unfortunately, clinical treatment for the disease using these factors is difficult -- these proteins are unable to cross the blood-brain barrier, and even if they could, their half-life is extremely short. A team of researchers lead by Jens Tornøe of NsGene A/S, in Denmark, has created a device that overcomes this problem. The solution is in the form of an implant containing cells that produce the neurotrophic factor, contained within a membrane supported by a polymer scaffolding, which allows the factor out and cell nutrients in. "Pre-symptomatic administration of a safe therapeutic treatment providing sustained delay or prevention of disease would be of great benefit to patients," says Dr. Tornøe.

Relevant Locations: Amsterdam, The Netherlands
Comment (1) Favorite (1)
Jackie Kelly It's both comforting and frustrating that our blood-brain barrier is this impenetrable. Glad to hear about this innovative way to cross it. I wonder if there are applications for other disorders. Maybe Alzheimer's or Parkinson's?
Jun 19, 2012