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Mar 27, 2012
Researchers create living human gut-on-a-chip
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Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created a gut-on-a-chip microdevice, lined by living human cells, that mimics the structure, physiology and mechanics of the human intestine -- even supporting the growth of living microbes. As a more accurate alternative to conventional cell culture and animal models, the microdevice could help researchers gain new insights into intestinal disorders, such as Crohn's disease and ulcerative colitis, and also evaluate the safety and efficacy of potential treatments. Building on the Wyss Institute's breakthrough "Organ-on-Chip" technology that uses microfabrication techniques to build living organ mimics, the gut-on-a-chip is a silicon polymer device about the size of a computer memory stick.

Relevant Locations: Boston, MA, USA
Related Organizations: Chata biosystems Inc (US)
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