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Patexia Research
Patent No. US 09249196
Issue Date Feb 2, 2016
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Patent 09249196 - Neisseria meningitidis antigens and compositions > Claims

  • 1. A composition comprising an immunostimulatory effective amount of aluminum salt adjuvant and a purified polypeptide comprising a fragment of the amino acid sequence of SEQ ID NO: 2536, wherein the fragment comprises 18 or more consecutive amino acids from the amino acid sequence, and wherein the purified polypeptide is immunogenic.
    • 2. The composition of claim 1 comprising the fragment, wherein the fragment comprises 20 or more consecutive amino acids from the amino acid sequence of SEQ ID NO: 2536.
      • 4. The composition of claim 2, in combination with a pharmaceutically acceptable carrier.
      • 6. The composition of claim 2, in further combination with a pH buffering agent.
    • 3. The composition of claim 1, in combination with a pharmaceutically acceptable carrier.
    • 5. The composition of claim 1, in further combination with a pH buffering agent.
    • 7. The composition of claim 1, wherein the composition is formulated as an injectable.
    • 8. The composition of claim 1, wherein the purified polypeptide is recombinant.
    • 9. The composition of claim 1, wherein the aluminum salt adjuvant comprises an aluminum hydroxide adjuvant.
    • 10. The composition of claim 1, wherein the aluminum salt adjuvant comprises an aluminum phosphate adjuvant.
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