Patent 10314845 - Benzimidazole derivatives as PI3 kinase inhibitors > Claims
1. A method for treating a susceptible PTEN-deficient neoplasm selected from prostate cancer, non-small-cell lung cancer, endometrial cancer, gastric cancer, melanoma, head and neck cancer, breast cancer and a glioma in a human in need thereof comprising the steps of: (a) analyzing a sample from said neoplasm to determine whether there is a PTEN deficiency in cells of said neoplasm; (b) selecting a human having said neoplasm with PTEN deficiency; and (c) administering a therapeutically effective amount the compound of formula or a pharmaceutically acceptable salt thereof to the human selected in step (b).